Adrenaline is our friend! It’s one of those hormones that floods our bodies when we severely injure ourselves, feel afraid, or do strenuous exercise. It’s known as “the fight or flight hormone” (along with some help from norepinephrine and dopamine). And it’s interchangeably referred to as adrenaline or epinephrine.

But what happens when too much pours into our bloodstream? We DIE! And that makes for a very interesting method of murder and can become the basis of a dramatic murder scene in writing.

We’ve all experienced an adrenaline rush in some form or another. From whatever cause, when our adrenal glands pump adrenaline (epinephrine) into our bloodstream, we experience: 1) a noticeable increase in strength, 2) no feeling of pain, 3) heightened senses, 4) a sudden burst of energy, and 5) our breathing and heart rate increases.

Such symptoms of extra adrenaline in our bodies may be in response to extreme fear, a life-threatening trauma (either to ourselves or others), or as a result of competitive sports participation. It helps us think clearly, react rapidly and appropriately, and dulls pain when needed. This experience is known as an “adrenergic storm” and is the basis of the fight or flight reaction.

Adrenaline, as an epinephrine drug, also treats severe allergic reactions since the drug narrows blood vessels to raise falling blood pressure. It also opens airway passages that may be constricted with associated wheezing. There are auto-injectors available for people who may experience such allergic reactions.

The drug is readily available in an intramuscular auto-injector mechanism as an adult dose of 0.3mg (the 1:1000 strength). Since I have asthma, I carry around an injector. I’ve not used it for an asthmatic episode, but I did use it once while experiencing a rather dramatic reaction to an antibiotic.

Recently, there has been much in the news about a certain drug manufacturer that dramatically increased the price of this live-saving drug from about $100US for a double pack to over $600US for that same pack. That tragedy is another whole blog in itself and I’ll leave that for another time since the backlash is still unfolding. For today, I’ll focus on this drug’s possible use as an intriguing murder weapon.

An overdose of adrenaline (epinephrine) flooding into our bodies can be LETHAL. At times, we’ve seen news reports of medical professionals mistakenly administering a wrong dose of epinephrine and killing the patient.

There are also reports of people using epinephrine as a weapon of murder! And the consequences of an epinephrine overdose can lead to complete cardiac arrest.

Initially, there’s a rapid onset of agitation, blood pressure spikes, the heart beats fast and irregular, slurred speech and confusion ensue, sometimes a severe headache is experienced—and then the person cascades into either a cerebral hemorrhage or cardiac arrhythmias prior to death.

Treatments to prevent the fatal outcome include administration of benzodiazepines and beta-blocker drugs, but administration should be immediate since epinephrine acts rapidly, especially if it is given intravenously.

So, with a readily available source, rapid onset and a deadly outcome, adrenaline could easily transition from friend to foe and provide an interesting murder weapon. That should create a rather dramatic murder scene involving either your protagonist or antagonist.

Thoughts? Comments? I’d love to hear them!